Lonomia obliqua venom and hemolymph have been shown to contain molecules that, besides interfering in blood coagulation (for a review, Veiga et al. ). Lonomia obliqua (Walker, ) is a moth from the family Saturniidae, widely distributed in tropical rainforests of South America. In its larval stage (caterpillar) it . Rev Assoc Med Bras (). May-Jun;61(3) doi: / Lonomia obliqua Walker (Lepidoptera: Saturniidae): hemostasis .

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Its venom has been the subject of numerous medical studies.

By the next day, this had resolved but she had generalized myalgia and ankle oedema and later haematuria and gingival haemorrhage. Caterpillar in Yasuni National ParkEcuador.

In other projects Wikimedia Commons Wikispecies. In its larval stage caterpillar it is characterized by bristles that cover the animal’s body.

In one study, by Pinto et al. After 24 and 48 h of treatment, cells were analyzed by the MTT method. On examination, she was pale and mildly jaundiced. Canadian Medical Association Journal. An antiapoptotic protein purified from the venom was also used in some analyses. Lonomia obliqua has a toxic venom which causes disseminated intravascular coagulation and a consumptive coagulopathy, which can lead to a hemorrhagic syndrome.

Lonomia obliqua – Wikipedia

MTT analyses indicate that L. Hemorrhagic syndrome associated with consumption coagulopathy, intravascular hemolysis and acute renal failure are some of the possible clinical manifestations related to poisoning by L. Articles using diversity taxobox Articles with ‘species’ microformats. Urine microscopy showed 25 non-fragmented red cells per high-power field. Exploring new molecules and activities from Lonomia obliqua caterpillars. This article has been cited by other articles in PMC.


The poison only takes effect in fairly large amounts; in order to experience the extreme effects caused by the toxins, a human victim would probably need to be stung at least 20 to times because each sting only injects a minute amount of venom. Proteases from Lonomia obliqua venomous secretions: Enhancement of Sf-9 cell growth and longevity through supplementation of culture medium with hemolymph. A catalog for the transcripts from the venomous structures of the caterpillar Lonomia obliqua: Brazilian Journal of Medical and Biological Research.

If blood products are required, they must be given cautiously to avoid fueling the constant consumptive coagulopathy.

In view of the results showing an increase in cell viability of UMG and HT cells, we tested different doses of a protein that has been shown to display antiapoptotic activity on Sf-9 cells Souza et al.

These mechanisms of increasing or decreasing cellular proliferation are extremely important for the understanding of the venom effects in different cell types and should be a research subject for future studies. The fact that the venom significantly increases the amount of viable cells, even when diluted in culture medium supplemented with 0.


Lonomia obliqua

Four days before, she had started to present hematuria. Some of the toxin components also result in direct toxicity to endothelium and tubular cells. Symptoms include local irritation, urticarial dermatitis, allergy, ocular injuries, osteochondritis, haemorrhage secondary coagulopathy and acute renal failure.

Email alerts New issue alert. To check if the same effects obtained in the UMG cell lineage would be observed in other cells, two other cell types were also used, both obtained from ATCC: Correspondence and offprint requests to: Olnomia treated with venom at doses that significantly increased the proliferation of UMG showed a decrease in nitric oxide production compared to the negative control.

Lonomia obliqua – Wikipedia tiếng Việt

Discussion Animal venoms are complex combinations of different active principles, causing diverse effects in human physiology when envenomation occurs. A central line was inserted and after the obliquw haemodialysis session she was given 10 ampoules of anti-lonomic horse serum.

Tissue Eng Part C Methods.